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2020年3期

Journal of Pharmaceutical Analysis訂閱

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Preface

• Preface for special issue on new analytical techniques and methods in drug metabolism and pharmacokinetics

Review Papers

• Current status and future directions of high-throughput ADME screening in drug discovery
• Current LC-MS-based strategies for characterization and quantification of antibody-drug conjugates
• Current status of in vivo bioanalysis of nano drug delivery systems

Original Articles

• Ultra-sensitive bioanalysis of the therapeutic peptide exenatide for accurate pharmacokinetic analyses at effective plasma concentrations utilizing UPLC-MS/MS
• Software-aided detection and structural characterization of cyclic peptide metabolites in biological matrix by high-resolution mass spectrometry
• Quantitation of DNA by nuclease P1 digestion and UPLC-MS/MS to assess binding efficiency of pyrrolobenzodiazepine
• Rapid bioluminescence assay for monitoring rat CES1 activity and its alteration by traditional Chinese medicines
• An ultra-sensitive and easy-to-use assay for sensing human UGT1A1 activities in biological systems

Short Communication

• Screening of the whole human cytochrome P450 complement(CYPome)with enzyme bag cocktails