Special Issue on‘‘Computational Cardiology’’

We are pleased to announce a special issue on‘‘Computational Cardiology’’of the journalGenomics,Proteomics&Bioinformatics(GPB),aiming to provide a platform for high-quality papers focusing on the topic and we invite submissions for this special issue(to be published in the Spring of 2016).Dr.Benjamin Meder(University of Heidelberg and German Center for Cardiovascular Research-DZHK,Germany)andDr.Andreas Keller(Saarland University, Germany)areGuest Editorsof this issue.

Cardiovascular diseases are the leading cause of death worldwide and subject of intensive biomedical research.The future success in dissecting their causes and mechanisms will depend on integrated research strategies utilizing both the results of highly-sophisticated unbiased‘‘omics’’technologies to understand the genetic,epigenetic,proteomic,and metabolomic disease contributions and classical hypotheses-driven molecular research strategies.These approaches already have provided an unprecedented volume of data,the analysis of which exceeds the capacity of scientists trained in molecular or clinical research.

This points to the need to accelerate the incorporation of expertise in bioinformatics and mathematics into the cardiovascular research strategy of the future to integrate biological information,known disease mechanisms,and high volume datasets from clinical phenotyping and omics analysis.Such a systemic computational approach integrating both the molecular defect and its many interacting components may lead to an entirely-novel understanding of the pathophysiology of cardiovascular diseases and may aid in the identification of novel diagnostics and treatment targets.

Importantly,we aim to cover multiple scales--starting from molecular diagnostics to proteomics to the understanding of whole cells and organs.Specifically,the topics of this special issue include:

? Genomics of cardiovascular diseases

? Transcriptomics of cardiovascular diseases

? Epigenetics of cardiovascular diseases

? Proteomics of cardiovascular diseases

? Metabolomics of cardiovascular diseases

? Computer-aided imaging of the heart(CT,MRI,Ultrasound)

? Multi-scale models of the heart

Original studies,reviews,methods,application notes,and reports on tools,etc.,are all welcome.We encourage your submission to the special issue on Computation Cardiology tillNovember 15,2015.Accepted submissions to this special issue will bepublished free of charge.

Manuscripts should be submitted online at http://ees.elsevier.com/gpb/.Please indicate that the submission is for this special issue.The Guide for Authors is available on this website as well,while manuscript template and EndNote Output style template can be found at gpb.big.ac.cn.

For further information,please contact us:

Dr.Benjamin Meder(Benjamin.Meder@med.uni-heidelberg.de);

Dr.Andreas Keller(andreas.keller@ccb.uni-saarland.de);

Editorial Office(editor@big.ac.cn).