張志強(qiáng)+王奕+鄒南安+丁紹純+崔甜甜+劉峰
【摘要】 目的:對(duì)MR波普(MR spectroscopy,MRS)在介入再開通術(shù)(經(jīng)皮腔內(nèi)血管成形術(shù))治療下肢動(dòng)脈硬化閉塞癥療效評(píng)估中的作用與價(jià)值進(jìn)行分析和探討。方法:選取2014年1月-2016年2月在本院接受治療的56例下肢動(dòng)脈硬化閉塞癥患者,依據(jù)隨機(jī)雙盲原則將其分為對(duì)照組和觀察組,每組28例。觀察組給予MRS檢查和經(jīng)皮腔內(nèi)血管成形術(shù)治療,對(duì)照組給予減影血管造影(DSA)檢查及常規(guī)保守治療。隨訪9個(gè)月,比較兩組臨床療效。結(jié)果:MRS檢查靈敏度為98.87%。觀察組治療成功率為96.43%,對(duì)照組為60.71%,差異有統(tǒng)計(jì)學(xué)意義( 字2=10.606,P<0.05)。治療后9個(gè)月,觀察組再次閉塞率明顯低于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義( 字2=5.453,P<0.05)。結(jié)論:MRS是評(píng)估介入再開通術(shù)治療下肢動(dòng)脈硬化閉塞癥療效的有效手段,安全、無創(chuàng)、準(zhǔn)確,推薦使用。
【關(guān)鍵詞】 MRS; 經(jīng)皮腔內(nèi)血管成形術(shù); 下肢動(dòng)脈硬化閉塞癥
【Abstract】 Objective:To analyse and discuss the value of MR spectroscopy(MRS) on therapeutic effect evaluation of interventional recanalization(percutaneous transluminal angioplasty) in treatment of lower extremity arterial occlusive disease.Method:From January 2014 to February 2016,56 cases of lower extremity arteriosclerosis in our hospital for treatment of occlusive disease were divided into the observation group and the control group according to randomized double-blind principle,28 cases in each group.The observation group was given MRS examination and percutaneous transluminal angioplasty treatment,the control group was given subtraction angiography(DSA) and conventional conservative treatment.After 9 months of follow-up,the clinical efficacy of two groups were compared.Result:The sensitivity of MRS was 98.87%.The treatment success rate of the observation group was 96.43%,and the control group was 60.71%,and the difference was statistically significant( 字2=10.606,P<0.05).9 months after treatment,reocclusion rate of the observation group was significantly lower than that of the control group,the difference was statistically significant( 字2=5.453,P<0.05).Conclusion:MRS is an effective method to evaluate the efficacy of interventional recanalization(percutaneous transluminal angioplasty) in the treatment of lower extremity arteriosclerosis obliterans,it is safe,noninvasive,accurate and recommended.
【Key words】 MRS; Percutaneous transluminal angioplasty; Lower extremity arteriosclerosis obliterans
First-authors address:Pingxiang Peoples Hospital,Pingxiang 337000,China
doi:10.3969/j.issn.1674-4985.2017.23.032
MR波普(MR spectroscopy,MRS)屬于一種無創(chuàng)血管檢查方式,具有較高的診斷準(zhǔn)確性,如今MRS在國(guó)外已得到廣泛認(rèn)可和使用,且大量研究反應(yīng)效果良好,具有安全、可靠、表達(dá)直觀、可反復(fù)操作等優(yōu)點(diǎn)[1-2],但調(diào)查發(fā)現(xiàn),我國(guó)關(guān)于MRS評(píng)估下肢動(dòng)脈硬化閉塞癥治療療效的研究尚處于起步階段[3-4],在國(guó)內(nèi)各大醫(yī)院尚未常規(guī)開展?;诖耍狙芯?014年1月-2016年2月本院接受治療的56例下肢動(dòng)脈硬化閉塞癥患者為研究對(duì)象,分組給予不同的治療方式,分析探討MRS的臨床應(yīng)用價(jià)值,以供交流與借鑒,現(xiàn)報(bào)道如下。
1 資料與方法
1.1 一般資料 選取2014年1月-2016年2月在本院接受治療的56例下肢動(dòng)脈硬化閉塞癥患者,所有患者均符合臨床關(guān)于下肢動(dòng)脈硬化閉塞癥的診斷標(biāo)準(zhǔn),出現(xiàn)不同程度的肢體冰冷、麻木、間歇性跛行等癥狀,且跛行長(zhǎng)度不大于400 m,堵塞部位均未觸及患者足背和脛后動(dòng)脈,患者肢體皮溫低于參考范圍。排除標(biāo)準(zhǔn):合并其他嚴(yán)重的器質(zhì)性疾病且可對(duì)本次研究結(jié)果造成嚴(yán)重影響的患者;患有嚴(yán)重的精神類疾病無法配合研究的患者。依據(jù)隨機(jī)雙盲原則將其分為對(duì)照組和觀察組,每組28例。觀察組男endprint
中國(guó)醫(yī)學(xué)創(chuàng)新2017年23期