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    KEYWORD INDEX(2020,Volume 36)

    2020-01-13 18:27:29
    中國病理生理雜志 2020年12期

    20-Hydroxyeicosatetraenoic acid 421

    2019 novel coronavirus/SARS-CoV-2 562

    27nt-miRNA 1745

    ABCA1/JAK2/STAT3 signaling pathway 1972

    Abdominal aortic aneurysm 769

    Activation 1396

    Activity regulation 2289

    Acute cardiogenic pulmonary edema 1255

    Acute cerebral ischemia 1389

    Acute hepatic injury 860

    Acute kidney injury 188 294 525 1450 2081

    Acute lung injury 507 681 725 913

    Acute lymphoblastic leukemia 977 1776

    Acute myocardial infarction 415

    Acute respiratory distress syndrome 562 568

    Acyl-coenzyme A:cholesterol acyltransferase 1 816

    Adipocytes 134

    Adiponectin 796

    Adipose differentiation 899

    Adipose tissue 2099

    Adrenergic signaling 747

    Adriamycin/doxorubicin 1543

    Aging 936

    Agkistrodon acutusvenom 991

    Airway inflammation 886

    Akt signaling pathway 552

    AKT/NF-κB signaling pathway 427

    AKT/STAT3 singaling pathway 612

    Albumin 681

    Alcohol 969

    Allele 354

    Alpiniae oxyphyllaeFructus 2212

    Alveolar type Ⅱepithelial cells 1825

    Alzheimer disease 1063 2198

    AMP-activated protein kinase 796 936

    AMPK/Nrf2/HO-1 signaling pathway 38

    AMPK/TFEB signaling pathway 1269

    Amyolid β-protein 1-40 1966

    Anacardic acid 200

    Andrographolide 628 977

    Anesthesia depth 475

    Angiogenesis 969 1422 1515

    Angiotensin Ⅱtype 1 receptor autoantibody 444

    Anhua dark tea 1274

    Anthocyanin 360

    Anti-silencing function 1B 1602

    Anti-tumor drugs 1133

    Apelin-13 134

    Aplastic anemia 1314

    Apolipoprotein E 1274

    Apoptosis 22 29 38 59 67 97 152 170 206 214 222 229 239 244 329 366 401 421 433 444 487 525 628 657 673 707 753 788 847 977 985 991 1006 1055 1082 1089 1110 1185 1199 1237 1368 1375 1404 1413 1450 1493 1616 1653 1745 1761 1776 1860 1928 1945 2005 2013 2043 2166 2212 2234

    ARMCX1 protein 170

    Arteriogenesis 1537

    Arthritis 693

    Asthma 886 1465 1502 1715 1818

    Astragaloside 2244

    Astragalus2198

    Astrocytes 501 1042

    ATAC-seq 2037

    ATF6/PERK-CHOP signaling pathway 1006

    Atheroscherosis 637 713 816 1020 1261 1327 1476 1515 1565 1754 1897

    Atherosclerosis 1928 1952 2093 2123 2133

    ATM protein 741

    ATP-binding cassette transporter A1 816 1952

    ATP-binding cassette transporters 206

    ATR protein 741

    Atrial natriuretic peptide 47

    Autism 837

    Autoimmune myocarditis 1729

    Autophagy 366 444 673 725 796 860 893 924 936 1014 1071 1199 1230 1269 1428 1439 1444 1493 1616 1825 1980 2020 2056 2081

    Autophagy-related protein 5 847

    B-lymphocyte stimulator 1294

    Bacterial meningitis 1161

    Baicalin 268 1294

    Batokines 1140

    Bcl-2 protein 2005

    Bcl-6 protein 2205

    Belinostat 552

    Bexarotene 1565

    Bezafibrate 519

    Bile acids 2086

    Bioinformatics 175 346 998 2037

    Biological behavior 1587

    Biomarkers 2264

    BIRC5 protein 2013

    Bladder cancer 82 612

    Bladder detrusor 2212

    Bladder outlet obstruction 301

    Blood dialysis 562

    Blood-brain barrier 2190

    Blueberry 360

    BMP-7/Smads pathway 316

    Body weight 1921

    Bone marrow mesenchymal stem cells 762

    Bortezomib 1482 2062

    Brain injuries 468

    Brain-derived neurotrophic factor 282

    Breast cancer 244 865 969 1587 1595

    Bronchial epithelial cells 507 557

    Brown adipose tissue 1140

    BTB and CNC homology 2 1776

    Burn 336

    Bushen-Huoxue prescription 700

    c-Met/AKT/mTOR signaling pathway 871

    c-Myc protein 234

    C1GALT1/Cosmc pathway 2050

    C1q/TNF-related proteins 1470

    C1q/tumor necrosis factor-related protein 3 1551

    C57BL/6 mice 1146

    Calcium channels 2212

    Calcium ion 532

    Calcium phosphate 769

    Calcium-activated chloride channel 2105

    Calpain-2 847

    Capsular polysaccharide 514

    Carboxyl terminus of heat shock protein 70-in?teracting protein 1368

    Cardiac contractility modulation 547

    Cardiac fibroblasts 1 1543

    Cardiac fibrosis 1 385 1531 1521

    Cardiac hypertrophy 1122

    Cardiac remodeling 2113

    Cardic myocytes 433

    Cardiomyocyte hypertrophy 200

    Cardiomyocytes 214 401 421 788 796 1014 1761

    Cardiopulmonary resuscitation 468

    Cardiovascular diseases 371

    Cartilage degeneration 700

    Caspase-1 598

    Catalase 1302

    Cathepsin C 2133

    Caveolin-1 2123

    CC chemokine receptor 2 969

    CC-223 234

    CCAAT/enhancer-binding protein homologous protein 222

    CCDC78gene 998

    CCN proteins 1902

    CD36/Src/ERK signaling pathway 1020

    CD68 1557

    Celastrol 487

    Cell cycle 164 234 495 707 1572 1579 1595

    Cell differentiation 762 1988

    Cell growth 977

    Cell invasion 252 2174

    Cell migration 252 619 810 871 1170 1192 1215 1224 1434 1487 1579 1887 2166 2174

    Cell proliferation 59 152 164 170 239 276 810 871 1071 1170 1396 1422 1595 1680 1690 1988 2005

    Cell viability 67 97 244 252 276 479 552 619 906 985 1082 1487 1572 1579 1602 1776 1789 1887 1945 2013 2043 2166 2174

    Cellular senescence 652

    Cerebral cortical nerve cells 673

    Cerebral ischemia-reperfusion 673 2190 2251

    Cerebrospinal fluid 1875

    Cervical cancer 67 170 1439

    Cervical squamous intraepithelial lesions 2300

    Cervical squamous-cell carcinoma 146

    Chaihu-Shugan decoction 1476

    Chemerin 1122

    Chemotherapy 175

    Chloroquine 1320

    Cholangiocarcinoma 961

    Cholesterol 53 1359

    Cholesterol efflux 1980

    Chondrocytes 1089

    Choroidal neovascularization 104

    Chronic heart failure 547

    Chronic hepatitis B 1833

    Chronic intermittent hypoxia 1631

    Chronic kidney disease 188

    Chronic obstructive pulmonary diseases 1302

    Chronic periodontitis 1308

    Chronic unpredictable mild stress 451

    Circular RNA 688

    Circular RNA_0000231 239

    Circular RNA_001131 1

    ClC-3 channel 1153

    ClC-3 chloride channel 495

    Clear cell renal cell carcinoma 1996

    Clinical application 1133

    Cluster of differentiation 14 539

    Cluster of differentiation 36 1269

    Co-stimulatory molecules 1314

    Cognitive dysfunction 1810

    Collagen type I alpha 1 chain 59

    Colon cancer 175

    Colorectal cancer 998 1215

    Complement 1115 1960

    Connexin 43 501 547

    Continuous renal replacement therapy 2081

    Cordyceps militarispolysaccharides 1754

    Coriaria sinicaMaxim′s extract 336

    Coronary artery 439

    Coronary artery atherosclerosis 1557

    Coronary artery disease 206

    Coronary atherosclerotic heart disease 1255 1470

    Coronary heart disease 408 2133

    Coronavirus disease 2019 568 573 1913

    Coxsackie virus B3 427

    CR6-interacting factor 1 401

    CREB/BDNF signaling pathway 1063

    Cromolyn sodium 693

    Crush injury syndrome 2220

    Cucurbitin E 886

    Cumulus cells 2294

    Cuprizone 1115

    Curcumin 860 1647 1867 2056

    CXC chemokine receptor 7 612

    Cyanidin 2113

    Cyclin D1 239

    Cycloastrogenol 385

    Cyclooxygenase-2 2159

    Cystathionine β-synthase 119

    Cysteine-rich protein 61 507

    Cytochrome b-245 alpha polypeptide 1302

    Cytochrome P450 epoxygenases 1661

    Cytokine storm 568 1913

    Cytokines 514

    Dasatinib 2166

    Deacetylation 1334

    Decellularized scaffold 762

    Demyelinating diseases 1115

    Dendritic cells 2093

    Dendritic spines 1049

    Deoxyribonuclease 913

    Depression 282 451 461 1049 1875 2264

    Dexmedetomidine 282 1185

    Diabetes mellitus 38 433 598 930 1368

    Diabetic cardiomyopathy 29 47

    Diabetic hepatopathy 519

    Diabetic kidney disease 1696

    Diabetic nephropathy 53 893 1639

    Diabetic retinopathy 577 1382 1515

    Differentiation 1020

    Dihydroartemisinin 1782

    DNA damage 487

    DNA damage repair 1667

    DNA damage response 741

    DNA double-strand breaks 741

    DNA methylation 119

    DNA-dependent protein kinase 741

    Dopamine 289

    Dopaminergic neurons 127

    Dorsal root ganglion 1153

    Double-edged sword 725

    Doxorubicin 552

    Drug development 1133

    Drug resistance 89 175

    Drug treatment 1502

    Dynamin-related protein 1 47 1110

    E-cadherin 1434

    E3 ubiquitin ligase ITCH 930

    Eca109 cells 1690

    Elderly patients 475

    Electrical remodeling 547

    Electro-acupuncture 1972

    Elemene 707

    End-stage renal disease 2068

    Endocrine 1140

    Endogenous cannabinoids 2020

    Endometrial cancer 2174

    Endometriosis 1892

    Endoplasmic reticulum stress 9 193 222 847 936 991 1006 1027 1071 1237 1375 2020

    Endothelial cells 17 652 713 1006 1351 1515 1537 2276

    Endothelial nitric oxide synthase 803 1739

    Endothelial-mesenchymal transition 316 893

    Endothelial-to-mesenchymal transition 822

    Endothelin receptors 779

    Endothelium-dependent relaxation 2159

    Endotoxin 294

    Enterohepatic circulation 2086

    Eosinophils 1818

    EphB2/ephrin-B1/NMDA receptor signaling pathway 1389

    Epidermal growth factor receptor 514

    Epidermis 753

    Epigallocatechin gallate 1769

    Epigenetics 1327 2099

    Epimedium2198

    Epithelial cells 2276

    Epithelial sodium channel 943

    Epithelial-mesenchymal transition 479 1422 1608

    Epoxyeicosatrienoic acids 1661

    Epstein-Barr virus 2030

    ERK1/2 signaling pathway 1224

    Erythroid differentiation 663

    Esophageal cancer 97 1690

    Esophageal carcinoma 75

    Esophageal squamous-cell carcinoma 1192

    Estriol 1281

    Ethyl pyruvate 2182

    Eukaryotic expression 1071

    Excitotoxicity 2182

    Exenatide 1921

    Exosome 371 378

    Exosomes 606 906 1014 1351 2074

    Experimental autoimmune encephalomyelitis 181

    Expression regulation 2289

    Extracellular matrix 719 762 1531

    Extracts of Herba Taxilli 1082

    F-box and WD repeat domain containing pro?tein 7 2234

    Farnesoid X receptor 2086

    Fasudil 1796 1803

    Fatty acid synthase 289 1892

    Fecal microbiota transplantation 1833

    Fenglong point 1972

    Ferroptosis 1261

    FEZF1-AS1 1945

    FHITgene 1493

    Fibroblast growth factor 9 214 1653

    Fibroblasts 2043

    Fibronectin 157

    Fibrosis 1458 1543

    Finasteride 323

    Fine particulate matter 810

    Flax lignan/secoisolariciresinol diglucoside 1631

    Flow cytometry 1396

    Foam cells 816 1230 1897 1980

    Forkhead box protein O1 294

    Formononetin 1434

    Forsythiaside A 1128

    FRT cells 2105

    Fructose 735

    Fucosylation 1192

    Fuzilizhong decoction 2258

    G-protein-coupled receptor 75 421

    Gabexate mesilate 2190

    Galectin-3 1557

    Galectin-9 1308

    Gastric cancer 152 2005 2013

    Gastric carcinoma 2030

    GATA binding protein-1 663

    GATA binding protein 5 415

    Gene chips 175

    Geniposide 1810

    Genomic instability 1493

    GINS complex subunit 2 2043

    Glioma 707 1887

    Glomerular epithelial cells 1860

    Glucagon-like peptide-1 1921

    Glucogen sythase 1769

    Glucose metabolism 1515

    Glucose transporter 2 1769

    Glucose-6-phosphate dehydrogenase 1769

    GlutathioneS-transferase kappa 1 1996

    Glycolipid metabolism 735

    Glycolysis 1572

    Golden hamsters 140

    Granulosa cells 2234

    Granulosa cells 2294

    Gynostemma pentaphyllum 713

    H19gene 2030

    H9C2 cells 444 1122 1249

    HaCaT cells 1854

    Heart 1237

    Heart failure 924 1034 1509 1938

    Heart function 1531

    Heat shock protein 90 1960

    Heat shock protein 90α 157

    Hedgehog signaling pathway 700

    Hemorrhagic shock 2074

    Hepatic fibrosis 719

    Hepatic injury 119

    Hepatic stellate cells 688 719

    Hepatitis B virus 1281 1721

    Hepatocellular carcinoma 252 1207 1487 1782 2283

    Hepatocytes 847

    Hepcidin 2198

    HET 0016 1170

    Heterodimer 1729

    High glucose 788 1608 2159

    High glucose and high free fatty acid 29

    High mobility group protein B1 1639

    High-density lipoprotein 206

    High-density lipoprotein cholesterol 1255

    High-mobility group protein B2 164

    High-throughput screening 2105

    Hippocampus 1049 1185 1389

    Hippocampus 461

    Histone acetylation 200

    Histone chaperones 1602

    Histone deacetylase 6 1334

    Histone deacetylases 557 2099

    Histone H3K36 trimethylation 525

    Histone methylaion 719

    Homocysteine 119

    Hormone-sensitive lipase 289 899

    HOTAIRgene 2030

    hsa-miR-145-5p 1413

    hsa-miR-346 2205

    hsa_circ_087631 2205

    HSYA 439

    HT22 cells 2198

    Human aortic endothelial cells 1928

    Human gingival fibroblasts 1867

    Human hemangioendothelial cells 1422

    Human induced pluripotent stem cells 877

    Human papillomavirus 2300

    Human peritoneal mesothelial cells 2068

    Human umbilical vein endothelial cells 193 822 1368 1739 1745

    Human vascular smooth muscle cells 810

    HuR protein 2283

    Hydrogen sulfide 652

    Hyperbaric oxygen 1063

    Hyperlipidemia 140 1972

    Hyperpolarization-activated cyclic nucleotidegated cation channels 827

    Hypertension 1345 1938

    Hyperthyroidism 1625

    Hyperuricemia 1551

    Hypoxemia 568 573

    Hypoxia 214 244 663 1351

    Hypoxia-hypercapnia pulmonary hypertension 316

    Hypoxia-inducible factor-1α 244 1537 1661

    Hypoxia/reoxygenation injury 1825

    Hypoxic ischemic encephalopathy 366

    Hypoxic postconditioning 1960

    Hypoxic-ischemic encephalopathy 2182

    Idiopathic pulmonary fibrosis 112

    IgA nephropathy 2050

    IGF-1R-Stat3 signaling pathway 1207

    IL-33/ST2 signaling pathway 468 2062

    IL-6/STAT3 signaling pathway 97

    Ilex cornutaaqueous extract 899

    ILK signaling pathway 336

    Immune 1340

    Immune function 1128 2050

    Immune imbalance 1913

    Immune inhibitory receptor 1314

    Immune response 394

    Immunomodulation 1465

    Inducible nitric oxide synthase 2159

    Indxyl sulfate 1014

    Infertility 2234

    Inflammation 22 53 104 112 301 309 854 913 1104 1185 1320 1551 1639 1647 1661 1960 1966 2062 2190 2258

    Inflammatory bowel disease 1096

    Inflammatory cytokines 1704

    Inflammatory factor 354

    Inflammatory factors 157 693 1844 2081

    Inflammatory response 427 507 514 557 637 681 1128 1625 1867

    Inflarnmation 1465

    Influenza A virus 1673

    Influenza virus 681

    Inositol 1,4,5-trisphosphate receptor 532

    Insulin 2139

    Insulin resistance 588 930 1661

    Insulin-like growth factor 1 receptor 1215

    Insulin-like growth factor 2 mRNA-binding pro?tein 3 75

    Insulin-producing cells 877

    Interferon gamma 1096

    Interleukin-1 receptor accessory protein 1729

    Interleukin-1 type II receptor 1729

    Interleukin-10 1153

    Interleukin-11 1531

    Interleukin-17 1096

    Interleukin-17A 1854

    Interleukin-18 1833

    Interleukin-1β 1082 1739

    Interleukin-21 2205

    Interleukin-33 1450

    Interleukin-38 1715

    Interleukin-4 539

    Interleukin-6 779

    Intermittent hypoxia 2212

    Interstitial lung disease 1715

    Intestinal barrier injury 1844

    Intestinal fibrosis 1096

    Intestinal flora 2050

    Intracerebral hemorrhage 1055

    Invasion 82 619 1192 1215 1224 1434 1579 1680 1789 1881 1887

    IOX1 719

    Ischemia-reperfusion 394

    Ischemia/reperfusion 525 644

    Ischemia/reperfusion injury 329 1960 2093

    Ischemic stroke 1709

    Isolated heart perfusion 1243

    Isolationin vitro2294

    Jieyuwan 1049

    Jinlida 1375

    Junctophilin-2 1034

    K562 cells 663 1988

    Kechuanning 1465

    Keloid 2043

    Keratinocytes 753

    Ketamine 1042

    Kidney diseases 378

    Kidney injury 1625

    Kidney proximal tubular cells 1104

    Klebsiella pneumoniae 514

    KLF6gene 97

    Klotho protein 816

    Knee osteoarthritis 157 700

    Krüppel-like factor 1 360

    Kupffer cells 854

    LH-EGFR signaling pathway 532

    Ligustilide 1422

    Linc00152 67

    LINC01503 619

    Lipid metabolism 588 637 1261

    Lipids 1921

    Lipoic acid 127

    Lipophagy 1980

    Lipopolysaccharide 1860 1867

    Lipopolysaccharides 507 837 1320

    Liraglutide 588

    Liver fibrosis 360 688

    Liver X receptor α 1359

    Local anesthetic 1667

    Long noncoding RNA 1761 1789 1908 1945 2030

    Long noncoding RNA ANRIL 1404

    Long-chain non-coding RNA MALAT1 82

    LoVo cells 479

    Low-density lipoprotein receptor 140

    Low-polarity ginsenoside F41988

    Lung adenocarcinoma 164 1680 1789 1881

    Lung cancer 619 985 1579 1715

    Lung cancer-associated transcript 1 1761

    Lung injury 309

    Lung ischemia/reperfusion injury 2056

    Lupeol 1413

    Lupus nephritis 188 1146 1647

    Lycorine 479

    Lysosome 1359

    M2 macrophage polarization 961

    Macrophage polarization 104

    Macrophage-derived foam cells 1754

    Macrophages 769 906 1014 1020 1308 1359 1897 1952 1972 1980

    Mailuoning 2220

    Mammalian target of rapamycin 234

    Mangiferin 657

    MAP4K3/MKK4/JNK signaling pathway 1055

    MAPK signaling pathway 886 1320

    MAPK/ERK signaling pathway 479

    MAPK/JNK/ERK signaling pathway 1602

    MAPKs signaling pathway 1966

    Mast cells 693

    Maternal immune activation 837

    Matrix metalloproteinase-1 268

    Matrix metalloproteinase-2 1557

    Matrix metalloproteinase 9 769 1434 1892

    Mechanical allodynia 1153

    Melanoma 606

    Melusin 408

    Mesenchymal stem cells 2037

    Mesenteric lymph 2074

    Metabolic diseases 735 1140

    Metabolic pathways 1526 2264

    Metabolism 1327 1509

    Metabolomics 1526 2264

    Metastasis 146

    Metformin 495

    Methicillin-resistantStaphylococcus aureus1673

    Mice 519 753

    Microglia 127 837 1170 1320

    MicroRNA 175 371 378

    MicroRNA let-7a 1055

    MicroRNA-124 1867

    MicroRNA-133 854

    MicroRNA-142-3p 1928

    MicroRNA-146b-5p 82

    MicroRNA-153 22

    MicroRNA-153-3p 1249

    MicroRNA-16 1875

    MicroRNA-19b 2139

    MicroRNA-204-3p 1761

    MicroRNA-206 871

    MicroRNA-214-5p 394

    MicroRNA-22 1014

    MicroRNA-22-3p 2068

    MicroRNA-223 1482

    MicroRNA-223-3p 1161

    MicroRNA-23b-3p 1653

    MicroRNA-24-3p 97 865

    MicroRNA-25-3p 1

    MicroRNA-3 1721

    MicroRNA-301a-3p 501

    MicroRNA-30a-5p 119

    MicroRNA-323 214

    MicroRNA-335-5p 619

    MicroRNA-363-3p 1945

    MicroRNA-375 877 1082

    MicroRNA-376c-3p 67

    MicroRNA-424-3p 1487

    MicroRNA-432-3p 657

    MicroRNA-433 1458

    MicroRNA-451a 663

    MicroRNA-485-5p 252

    MicroRNA-519d-3p 1789

    MicroRNA-556-3p 2174

    MicroRNA-626 1404

    MicroRNA-7-5p 1860

    MicroRNA-9-5p 2148

    MicroRNA-92a 2139

    MicroRNA-92b-5p 1639

    Microvascular permeability 644

    Midkine 1207

    Mifepristone 89

    Migration 82

    MIN6 cells 2139

    Minimally modified low-density lipoprotein 779

    Mitochondria 924 1110

    Mitochondrial autophagy 2251

    Mitochondrial calcium uniporter 433

    Mitochondrial damage 1696

    Mitochondrial division inhibitor-1 1115

    Mitochondrial dysfunction 366 421 1122

    Mitochondrial energy metabolism 713

    Mitochondrial fission 47

    Mitochondrial fusion 2113

    Mitochondrial injury 294

    Mitochondrial membrane potential 487 977

    MNX1 antisense RNA 1 1908

    Monocyte chemoattractant protein-1 969

    Monocytes 1255 1482

    Monocytes/macrophages 1327 1521

    Morphine 9

    Mortalin 146

    Mouse embryonic fibroblasts 606

    Multiple myeloma 487

    Multiple sclerosis 181

    Myeloid differentiation factor 88 1450

    Myeloperoxidase 309

    Myocardial cells 657

    Myocardial dysfunction 1243

    Myocardial fibrosis 1938

    Myocardial infarction 644 1027 1521 2093

    Myocardial injury 22 38 394 573

    Myocardial protection 9

    Myocardial remodeling 2093

    Myocardin-related transcription factor-A 673

    Myocardium 408

    N-arachidonic acid aminoethanol 2020

    N-palmitoylethanolamine 451

    NADPH oxidase 4 577

    Nasopharyngeal carcinoma 346

    Nasopharyngeal carcinoma cells 495

    Natural killer T cells 1345

    Necroptosis 1104

    Necrotizing enterocolitis 2227

    Neonatal rat 1796

    Neoplasm invasion 1493

    Nesfatin-1 2227

    Neural stem cells 1396

    Neurogenesis 1389

    Neurons 827 1055 1161

    Neurons 366

    Neuropathic pain 1153

    Neuropeptides 693

    Neuroprotection 1709

    Neurotoxicity 1667

    Neurovascular unit 1709

    Neutrophil extracellular traps 913

    NF-κB P65 signaling pathway 1690 1796

    NF-κB signaling pathway 557 886 1104 1170 1320 1647

    NF-κB/cyclin D1 signaling pathway 1595

    Nicotine 104 1287

    Nicotinic acetylcholine receptors 1287

    Nicotinic acid 1359

    Niemann-Pick C1 protein 1359

    Niflumic acid 1887

    Nintedanib 112

    Nitric oxide 17

    NLRC3 protein 985

    NLRP3 inflammasome 181 309 577 936 1161 1631 1673

    NLRP3 protein 53

    NLRP3 signaling pathway 1647

    NLRP3/IL-1β signaling pathway 1089

    Non-alcoholic fatty liver 1274 1902

    Non-alcoholic fatty liver disease 588 2258

    Non-small-cell lung cancer 239 1224

    NontypeableHemophilus influenzae557

    Notch signaling pathway 260 2220

    Nrf2/ARE signaling pathway 1249

    Nrf2/ARE/HO-1 signaling pathway 2182

    Nuciferine 1230

    Nuclear factor E2-related factor 2 29 657

    Nuclear factor-κB 385 2159

    Nuclear factor-κB-inducing kinase 1302

    Nuclear translocation 1269

    Nucleotide-binding oligomerization domainlike receptor protein 3 854 1482 2068

    Obesity 899 1140 1661 1902 2234

    Obesity-related kidney disease 188

    Obstructive nephropathy 301

    Olapanib 89

    Oligodendrocytes 1115

    Oncolytic virus M1 950

    Oocyte meiosis 532

    Oocytes 918

    Optic atrophy protein 1 2113

    Organic solute transporter α/β 2086

    Osteoarthritic chondrocytes 1082

    Osteoarthritis 1089

    Osteoblasts 598

    Osteogenic differentiation 2037

    Osteoporosis 598

    Osteosarcoma 552 628

    Ovarian cancer 59 229 1434 1428 2020

    Ovarian epithelial cancer 89

    Oxidative damage 1274

    Oxidative stress 9 29 38 112 134 193 385 401 444 568 1249 1368 1404 1509 1616 1625 1631 1761 1860 2056 2190 2244

    Oxidized low-density lipoprotein 1230 1327 1745 1897

    Oxygen-glucose deprivation/reoxygenation 1178

    P-selectin glycoprotein ligand-1 188

    p16 protein 2300

    p21-activated protein kinase 4 394

    P2Y2purinergic receptor 2105

    p38 MAPK signaling pathway 53 200 779 810

    P65 protein 1938

    Paeonol 1487 1854

    Pain 693

    Palmitic acid 401 803

    Palmitoylation 1269

    Panax notoginseng saponins 140 1178

    Panc-1 cells 1199

    Pancreatic ductal adenocarcinoma 260

    Pancreatic fibrosis 268

    Pancreatic kininogenase 1616

    Pancreatic progenitor cells 276

    Pancreatic stellate cells 260

    Papillary thyroid carcinoma 871

    Paracellular pathway 2276

    Paraventricular nucleus 2148

    Parkin 2251

    Parkinson disease 127 289 1042 1404

    Particulate matter 2.5 1526

    Pathogenesis 2264

    PD-L1 protein 1704

    Perfluorooctane sulfonates 309

    Periapical diseases 539

    Perilipin 1 899

    Perilipin 3 1881

    Perioperative neurocognitive disorders 1185

    Peritoneal dialysis 2068

    Periventricular leukomalacia 1796

    PERK signaling pathway 9

    PERK/eIF2α singaling pathway 991

    Peroxisome proliferator-activated receptor α 451

    Peroxisome proliferator-activated receptor-γ 637 899 1608

    Peroxisome proliferator-activated receptors 519 1509

    Phenotypic switching 1966

    Phenotypic transformation 1345

    Phenylephrine 200

    Phosphatidylinositol 3-kinase 2289

    Phosphoglycerate mutase family member 5 1110

    Phospholipase A2-X 1818

    Phosphorylation 803 1739

    PI3K/AKT signaling pathway 336 788 1487 1782

    PI3K/AKT/mTOR signaling pathway 282 329 1199 1230 1428

    Pim1/eNOS signaling pathway 17

    Pinocembrin 1006

    Pirfenidone 112

    Plaque stability 1557

    Platelet-derived growth factor receptor α 918

    Platelet-derived growth factor receptor β 1345

    Platelet-derived growth factor subunit A 918

    Platelet-rich plasma 1089

    Polycystic ovary syndrome 906 2244

    Porphyromonas gingivalis 1867

    Post-operative cognitive dysfunction 475

    Postmenopausal women 1255

    PPARγ-LXRα-ABCA1/ABCG1 signaling path?way 1754

    Precise quantification 1721

    Prefrontal cortex 451 1049

    Premature infants 2227

    Premature labor 1803

    Prenatal exposure 323

    Primary biliary cholangitis 2205

    Primary culture 753 2294

    Primer probe 1721

    Pristane 1146

    Procaine 612

    Prognosis 146 1881 2013 2081

    Proliferating cell nuclear antigen 1892

    Promoter 415

    Proprotein convertase subtilisin/kexin type 9 140

    Prostaglandin E1 1027

    Prostate cancer 1572 1602

    Prostate carcinoma 1413

    Protein kinase B 652

    Protein phosphatase 2A 803

    Protein phosphatase 4 803

    Protocadherin 10 1595

    Psoriasis 1854

    PTEN protein 1608 2289

    PTEN-induced putative kinase 1 2251

    Pterostilbene 1439

    Pulmonary artery endothelial cells 316

    Pulmonary edema 562

    Pulmonary hypertension 1302

    Pulsatilla saponin A 865

    Purple sweet potato anthocyanin 1844

    Pyroptosis 301 598 1178

    Pyruvate dehydrogenase kinase 4 1572

    Quantitative acetylproteomics 1996

    Quercetin 644 2251

    Quiescence 1396

    Rab11-family interacting protein 4 1215

    Radiosensitivity 67 707 865

    Radiotherapy 1782

    RadixPuerariae2198

    Randomly arranged collagen fibers 762

    Rapamycin 1709

    Raphe nuclei 1875

    RAS signaling pathway 1587

    Ras-relate C3 botulinon toxin substrate 1 606

    Rats 360 1128 1237

    Reactive oxygen species 433 577

    Receptor-interacting protein 1 1104

    Receptor-interacting protein 2 1199

    Recombinant adeno-associated virus serotype 9 1938

    Recombinant human progranulin 1071

    Regional cerebral oxygen saturation 475

    Regression analysis 408

    Regulatory T cells 1913

    Relaxation 439

    Renal cancinoma 2166

    Renal fibrosis 188 1616

    Renal inflammatory injury 1631

    Renal interstitial fibrosis 893

    Renal microvascular endothelial cells 1375

    Renal tubular epithelial cells 294 1608

    Renin-angiotensin system 134

    Replication 1281

    Reproductive health 1340

    Reproductive organs 323

    Respiratory diseases 943

    Resveratrol 229 893 1161

    Retinoic acid X receptor 1825

    Retinoid X receptor α 1565

    Retroperitoneal white adipose tissue 289

    Reverse cholesterol transport 1754 2123

    Rheumatoid arthritis 354 1294 1482 1653 2062

    Rho-associated coiled-coil kinase 788

    Rho/ROCK signaling pathway 1803

    Rho/ROCK2 signaling pathway 1796

    Rictor 1928

    Ring finger protein 2 865

    RNA interference 276

    RNA-binding proteins 2283

    ROCK/JNK signaling pathway 1476

    RT-qPCR 950 1721

    SARS-CoV-2 1340 1913

    SASH1 protein 2174

    SATB1 protein 346

    Scavenger receptors 1897 1952

    Scutellarin 1860

    Secondary pneumonia 1673

    Semaphorin 4D 1465

    Sepsis 1243 1450 1945

    Serotonin transporter 1875

    Serum and glucocorticoid-regulated kinase 1 301

    Sex determining region Y-box 5 252

    Sex hormones 2244

    Sexual developmental disorder 323

    SH-SY5Y cells 1178

    Shear stress 17

    SHI-1 cells 1988

    Signal transducer and activator of transcription 3 276

    Signaling pathways 1696

    SiHa cells 170

    Silent information regulator 1 644

    Simvastatin 1690

    Single nucleotide polymorphism 354 415 1302 2030

    Sinomenine 1404 1653

    SIRT1-FoxO signaling pathway 1439

    SIRT1/AMPK signaling pathway 588

    Sirt3-SOD2-ROS signaling pathway 229

    Skeletal muscle 1921

    Sleep deprivation 1810

    Smad3 protein 822

    Small-conductance calcium-activated potassium channels 2148

    Soluble uric acid 1444

    Sorafenib 222

    SORBS2 protein 22

    Sperm 1340

    Spermatogenesis 323

    Sphingosine 1-phosphate 822

    Sphingosine kinase 1 1224

    Spinal cord injury 461

    Spinal dorsal horn 827

    Spleen tyrosine kinase 961

    Splicing factor 3B subunit 1 1587

    Spontaneously hypertensive rats 1476

    Stanniocalcin-1 2005

    Stanniocalcin 2 1382

    STAT3 singaling pathway 1854

    Stellate ganglion block 2074

    Stem cells 1287

    Stemness 89

    Sterile inflammation 1543

    Stress 747

    Suberoylanilide hydroxamic acid 222

    Substrates 1334

    Sulodexide 577

    SUMO-specific protease 3 769

    Survivin 234

    Susceptibility 415 2030

    Swimming 1892

    Sympathoexcitation 2148

    Synapses 461

    Synaptic damage 1063

    Synoviocytes 1653

    SYNTAX score 1255

    Systemic lupus erythematosus 1146

    T helper 17 cells 1913

    T-cell immunoglobulin and mucin domain-con?taining protein-3 1308

    T-tubule 1034

    Tandons 762

    Tanshinone ⅡA 1261

    TaqMan 950

    Targeted therapy 961

    Testicular torsion 329

    Testis 1340

    Tetrandrine 1428

    TGF-β1/SMAD2 signaling pathway 1458 1565

    TGF-β1/Smads signaling pathway 688

    TGF-β1/TAK-NF-κB signaling pathway 268

    Th17 cells 1294

    The Cancer Genome Atlas 998

    Theca cells 906

    Thermogenesis 2099

    Thioredoxin 681

    Thioredoxin-interacting protein 1631

    THP-1 cells 1020

    Tight junction 2276

    Tight junction protein 1844

    Tissue Doppler imaging 1243

    Tissue inhibitor of metalloprotease-1 268

    TLR4/NF-κB p65 signaling pathway 2258

    TLR4/NF-κB signaling pathway 1810

    TMT-tagged quantitative proteomics 346

    Toll-like receptor 4 637 837 1444 1551 1833 2227

    Tongue squamous carcinoma 991

    Tongxinluo 1375

    Trained immunity 1327

    Transcription 1281

    Transcription factor 735

    Transcriptional intermediary factor 1γ 1579

    Transcriptional regulation 735

    Transforming growth factor-β 385 822

    Transforming growth factor-β1 336

    Transient receptor potential cation channel sub?family M member 8 1680

    Transient receptor potential cation channel sub?family V member 1 1502

    Transverse aortic constriction 2113

    Trauma 1237

    Tricellulin 2276

    TrimethylamineN-oxide 193 1034

    Tripartite motif-containing protein 25 75

    Tripartite motif-containing protein 8 29

    Tripterine 2043

    Tripterygium wilfordiimultiglucoside 2050

    Tropomyosin-related kinase B 282

    TSTA3 protein 1192

    TTN antisense RNA 1 1789

    Tuberculosis 1715

    Tubular epithelial cells 1444

    Tubulin 1034

    Tumor 747 1515 1908

    Tumor immune 1704

    Tumor microenvironment 1704

    Tumor necrosis factor ligand-related molecule 1A 1096

    Tumor necrosis factor-α 539 1153 2133

    Tumor xenograft model 1133

    Type 2 diabetes mellitus 1470 1769 2148

    Ubiquitin proteasome system 930

    Ubiquitination 75

    Ulcerative colitis 1128 1844

    Umbilical cord mesenchymal stem cells 1351

    Unilateral ureteral obstruction 1616

    Uremia 1014

    Uric acid 134 1110

    Urine 378

    Vascular endothelial cells 1551 1945

    Vascular endothelial growth factor 1382 1422

    Vascular smooth muscle cells 1345 1565 1966

    Vasculitis 573

    Ventricular remodeling 1027

    Viral myocarditis 427

    Voltage-gated K+channels 439

    Voltage-gated sodium channels 1153

    Water-salt balance 943

    Wendan decoction 1952 2123

    White matter injury 1803

    Wnt signaling pathway 628

    Wnt/β-catenin signaling pathway 2220

    Wogonoside 427

    Xingnao enema fluid 468

    Xuebijing 329

    Yangjing-Zhongyu decoction 918

    Yes-associated protein 1537

    Youguiwan 157

    Zebrafish 1133

    α-Synuclein 1042

    β1,3-N-actetylglucosaminyltransferase 8 152

    β1-Adrenergic receptor autoantibody 796

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