陳素云 吳倩紅 陳利慶 呂永革 趙志清
【摘要】 目的:分析和總結(jié)可逆性胼胝體壓部病變綜合征的臨床與MRI表現(xiàn)。方法:選擇筆者所在醫(yī)院2015年1月-2018年8月收治的10例可逆性胼胝體壓部病變綜合征患者作為研究對(duì)象,回顧性分析患者的臨床資料和MRI資料。結(jié)果:可逆性胼胝體壓部病變綜合征的主要臨床表現(xiàn)為發(fā)熱、頭暈、頭痛、咳嗽、嘔吐、意識(shí)障礙、肢體麻木、行為異常等。行MRI掃描后,可見大多數(shù)患者胼胝體壓部病灶形狀為圓形或橢圓形,少數(shù)為長(zhǎng)條形或斑片狀,且病灶邊界清楚,呈孤立性,主要位于中央?yún)^(qū)對(duì)稱性。FLAIR與T2WI均為稍高信號(hào),T1WI為稍低信號(hào)或等信號(hào),DWI呈明顯均勻高信號(hào),擴(kuò)散系數(shù)(ADC)圖表現(xiàn)為低信號(hào),所有患者均未見明顯囊性和壞死改變,病變周圍無明顯占位效應(yīng)及水腫。行增強(qiáng)掃描后,病灶未出現(xiàn)明顯強(qiáng)化。經(jīng)MRI檢查后,根據(jù)檢查結(jié)果給患者提供對(duì)癥的抗感染、抗病毒治療1~4周后,再對(duì)患者行MRI檢查,上述MRI表現(xiàn)消失。
結(jié)論:可逆性胼胝體壓部病變綜合征病因復(fù)雜,且缺乏特異性的臨床表現(xiàn),通過對(duì)具有前驅(qū)癥狀的患者行MRI檢查,根據(jù)MRI表現(xiàn)才能盡早對(duì)患者確診和治療,進(jìn)而才能提高其預(yù)后效果。
【關(guān)鍵詞】 可逆性胼胝體壓部病變綜合征; 臨床表現(xiàn); MRI
doi:10.14033/j.cnki.cfmr.2019.11.025 文獻(xiàn)標(biāo)識(shí)碼 B 文章編號(hào) 1674-6805(2019)11-00-03
Clinical and MRI Findings of Reversible Corpus Callosum Lesion Syndrome/CHEN Suyun,WU Qianhong,CHEN Liqing,et al.//Chinese and Foreign Medical Research,2019,17(11):-61
【Abstract】 Objective:To analyze and summarize the clinical and MRI findings of reversible corpus callosum lesion syndrome.Method:Ten patients with reversible corpus callosum lesion syndrome admitted to our hospital from January 2015 to August 2018 were selected as subjects.The clinical data and MRI data of the patients were retrospectively analyzed.Result:The main clinical manifestations of reversible corpus callosum lesion syndrome were symptoms such as fever,dizziness,headache,cough,vomiting,disturbance of consciousness,numbness of the limbs,and abnormal behavior.After MRI scan,it could be seen that the shape of the lesions of the corpus callosum was circular or elliptical in most patients,and a few were long or patchy,and the lesions were clearly and isolated,mainly located in the central region.FLAIR and T2WI were slightly higher signals,T1WI was slightly lower signal or equal signal,DWI was obviously uniform high signal,diffusion coefficient(ADC) diagram showed low signal,and all patients had no obvious cystic and necrotic changes around the lesion.No obvious placeholder effect and edema.After the enhanced scan,there was no significant enhancement of the lesion.After MRI examination,according to the results of the examination to provide patients with symptomatic anti-infective,anti-viral treatment 1-4,and then MRI examination of the patient,the above MRI performance disappeared.Conclusion:Reversible corpus callosum lesion syndrome is complicated and lacks specific clinical manifestations.MRI examination of patients with prodromal symptoms can confirm and treat patients as early as possible according to MRI performance,so as to improve their prognosis.
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