鄭淑芬
【摘要】 目的:探索優(yōu)質(zhì)護理配合唑來膦酸注射液治療老年骨質(zhì)疏松癥的臨床效果。方法:選擇筆者所在醫(yī)院與2017年1月-2018年4月收治的老年骨質(zhì)疏松癥患者160例,將患者隨機分為兩組,對照組行常規(guī)護理配合唑來膦酸注射液滴注,研究組行優(yōu)質(zhì)護理合唑來膦酸注射液滴注,對比兩組的骨密度情況及對護理服務(wù)的滿意率。結(jié)果:研究組治療后的腰椎、髖骨的骨密度為(0.895±0.064)、(0.869±0.127)g/cm3,高于對照組的(0.785±0.073)、(0.782±0.104)g/cm3(P<0.05);研究組不良反應(yīng)發(fā)生率6.2%,低于對照組的17.5%(P<0.05);研究組對護理服務(wù)滿意率為93.8%,高于對照組的81.3%(P<0.05)。結(jié)論:采用優(yōu)質(zhì)護理配合唑來膦酸注射液治療老年骨質(zhì)疏松癥能夠提高骨密度,降低不良反應(yīng)的發(fā)生率,增加患者對護理服務(wù)的滿意度,具有積極的應(yīng)用效果,適合推廣應(yīng)用。
【關(guān)鍵詞】 唑來膦酸注射液 優(yōu)質(zhì)護理 骨質(zhì)疏松癥 不良反應(yīng)
doi:10.14033/j.cnki.cfmr.2020.01.039 文獻標(biāo)識碼 B 文章編號 1674-6805(2020)01-00-03
[Abstract] Objective: To explore the clinical effect of high quality nursing combined with Zoledronic Acid Injection in the treatment of senile osteoporosis. Method: A total of 160 elderly osteoporosis patients in our hospital and admitted from January 2017 to April 2018 were randomly divided into two groups. The control group received routine nursing combined with Zoledronic Acid Injection, and the study group received high-quality nursing combined with Zoledronic Acid Injection. The bone mineral density and satisfaction rate of nursing service were compared between the two groups. Result: Bone mineral density of lumbar spine and hip in the study group were (0.895±0.064), (0.869±0.127) g/cm3, higher than (0.785±0.073), (0.782±0.104) g/cm3? in the control group (P<0.05). The incidence of adverse reactions was 6.2%, less than 17.5% in the control group (P<0.05). The satisfaction rate of nursing service was 93.8%, higher than 81.3% in the control group (P<0.05). Conclusion: high quality nursing combined with Zoledronic Acid Injection can improve the bone mineral density, reduce the incidence of adverse reactions, and increase the satisfaction of patients with nursing services.
[Key words] Zoledronic Acid Injection Quality nursing Osteoporosis Adverse reactions
First-authors address: Zhangzhou Hospital of Traditional Chinese Medicine, Zhangzhou 363000, China
骨質(zhì)疏松癥是由于機體骨量低下、骨微結(jié)構(gòu)損壞導(dǎo)致骨脆性增加,容易發(fā)生骨折的一種全身性骨病,其特征為骨強度下降、骨折風(fēng)險性增加,其中骨強度為骨礦密度和骨質(zhì)量[1-3]。老年骨質(zhì)疏松是最常見的一種骨質(zhì)疏松癥。老年骨質(zhì)疏松后受外力后極易發(fā)生骨折,且恢復(fù)困難,病殘率及死亡率較高[4-5]。為改善這一現(xiàn)狀,筆者所在醫(yī)院選擇探討優(yōu)質(zhì)護理配合唑來膦酸注射液用于治療老年骨質(zhì)疏松癥的應(yīng)用價值。
1 資料與方法
1.1 一般資料
選擇筆者所在醫(yī)院2017年1月-2018年4月收治的老年骨質(zhì)疏松患者160例,納入標(biāo)準(zhǔn):經(jīng)骨密度測量確診為骨質(zhì)疏松,年齡65~85歲。排除標(biāo)準(zhǔn):合并心、肝、腎等疾病者,合并骨腫瘤,患有精神疾病無法做出理智的判斷。患者對本次研究均知情同意。將其隨機分為兩組,對照組80例,男42例,女38例;年齡66~82歲,平均(62.54±3.21)歲。研究組80例,男41例,女39例;年齡65~81歲,平均(62.09±2.84)歲。兩組患者基本資料比較,差異無統(tǒng)計學(xué)意義(P>0.05),有可比性。
1.2 方法
治療方法:兩組均應(yīng)用唑來膦酸注射液(密固達)治療(生產(chǎn)廠家:Presbius Kabi Austria GmbH,批準(zhǔn)文號H20181132),治療前需確?;颊叩募◆宄蚀笥?5 ml/min,患者對磷酸鹽無過敏史,無感冒、發(fā)燒癥狀;5 mg唑來膦酸注射液用100 ml氯化鈉注射液稀釋后靜脈輸注,恒定滴速滴注(40~60 ml /min),滴注時間>15 min,唑來膦酸注射液輸注過程中不能與含鈣的液體接觸,不能與其他液體混合滴注,若溶液中出現(xiàn)微粒時禁止使用[6]。