0.05);兩組5年總生存"/>
許子志 黃國聰 許東興
【摘要】 目的:探究保留皮膚的乳腺癌改良根治術后即刻乳房再造與改良根治術的治療效果。方法:將2011年4月-2014年6月入院就診的100例乳腺癌患者為研究對象,根據(jù)手術方法不同將其劃分為對照組和觀察組,每組50例。對照組予以改良根治術治療,觀察組行保留皮膚的乳腺癌改良根治術后即刻乳房再造。比較兩組患者術后并發(fā)癥情況、5年總生存率、5年無病生存率及生活質量。結果:兩組患者術后皮下積液、皮瓣壞水及上肢水腫等并發(fā)癥發(fā)生率比較,差異無統(tǒng)計學意義(P>0.05);兩組5年總生存率及無病生存率比較,差異無統(tǒng)計學意義(P>0.05);觀察組生活質量評分高于對照組,差異均有統(tǒng)計學意義(P<0.05)。結論:實施保留皮膚的改良根治術后即刻乳房再造的方式與改良根治術療效相當,術后并發(fā)癥發(fā)生率較低、5年生存率及5年無病生存率均較高。但保留皮膚的改良根治術后即刻乳房再造可提升術后患者生活質量,臨床價值顯著,值得推廣。
【關鍵詞】 乳腺癌 即刻乳房再造 保留皮膚 改良根治術 效果
[Abstract] Objective: To investigate the therapeutic effects of immediate breast reconstruction after skin preserving modified radical mastectomy and modified radical mastectomy. Method: A total of 100 cases of breast cancer patients admitted to hospital from April 2011 to June 2014 were selected as the study subjects. According to different surgical methods, they were divided into the control group and the observation group, with 50 cases in each group. The control group was treated with modified radical mastectomy, and the observation group was treated with immediate breast reconstruction after skin preserving modified radical mastectomy. The postoperative complications, 5-year overall survival rate, 5-year disease-free survival rate and quality of life were compared between the two groups. Result: There were no significant differences in the incidence of postoperative complications such as subcutaneous hydrops, skin flap bad water and upper extremity edema between the two groups (P>0.05). There were no significant differences in the 5-year overall survival rate and 5-year disease-free survival rate between the two groups (P>0.05). The quality of life scores of the observation group were higher than those of the control group, and the differences were statistically significant (P<0.05). Conclusion: Immediate breast reconstruction after skin preserving modified radical mastectomy is as effective as modified radical mastectomy, with lower incidence of postoperative complications, higher 5-year survival rate and 5-year disease-free survival rate. However, immediate breast reconstruction after skin preserving modified radical mastectomy can improve the quality of life of patients after operation, which has significant clinical value and is worth popularizing.
乳腺癌作為一種乳腺腺上皮組織的惡性腫瘤,已成為當今女性的健康殺手,對其生活質量造成嚴重的影響。乳腺癌99%發(fā)于女性,其發(fā)病率逐年呈急速上升趨勢[1],其病因包括遺傳、激素、生殖、營養(yǎng)等多方面因素[2]。近年來,該病年輕化趨勢愈來愈嚴重[3],許多乳腺癌患者既想進行根治,又對自身美觀度抱有強烈的需求。目前,針對乳腺癌的治療手段多采用改良根治術,許多患者心理上難以接受手術后自身缺陷,寧愿放棄治療,導致病情惡化最終死亡。如何對患者徹底根除腫瘤的同時,又能保持自身美觀,成為現(xiàn)階段廣大醫(yī)療工作者的難題。針對這一問題,回顧性分析了筆者所在醫(yī)院100例乳腺癌患者臨床治療情況及預后情況,現(xiàn)具體報告如下。
綜上所述,對乳腺癌患者實施保留皮膚的改良根治術后即刻乳房再造的方法與改良根治術療效相當,術后并發(fā)癥發(fā)生率較低、5年生存率及無病生存率均較高。改良根治術后即刻乳房再造可提高患者后續(xù)生活質量,臨床價值顯著,值得推廣。
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(收稿日期:2019-09-24) (本文編輯:桑茹南)