邱建軍 盧玲 魏玉慧
【摘要】目的 探討急性心肌梗死心肺復(fù)蘇后緊急介入治療的療效。方法 回顧性分析15例存在心肺復(fù)蘇史行急診經(jīng)皮冠脈介入治療急性心肌梗死患者的各項(xiàng)臨床資料。結(jié)果 15例患者經(jīng)心肺復(fù)蘇治療后均恢復(fù)自主心率、自主呼吸,神志逐漸轉(zhuǎn)清。介入治療組住院時(shí)間與病情穩(wěn)定時(shí)間顯著短于溶栓組,左室射血分?jǐn)?shù)顯著大于溶栓組,差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 采用急診經(jīng)皮冠脈介入治療對(duì)心肺復(fù)蘇后急性心肌梗死患者來說是一種可靠安全的治療方法,值得臨床推廣。
【關(guān)鍵詞】緊急介入治療;急性心肌梗死;心肺復(fù)蘇
【中圖分類號(hào)】R542.22 【文獻(xiàn)標(biāo)識(shí)碼】B
Discus the curative effect of emergency interventional therapy in the treatment of acute myocardial infarction after cardiopumonary tesuscitation
Qiu Jian-jun,Lu Ling,Wei Yu-hui
(People's Hospital of Xinjiang Aletai area, Department of internal medicine2,
Xinjiang Aletai 836599,China)
【Abstract】Objective To study the patients with acute myocardial infarction after cardiopulmonary resuscitation (CPR) in clinical effect of emergency interventional therapy. Methods A retrospective analysis of 15 cases exist cardiopulmonary resuscitation (CPR) Shi Hang emergency percutaneous coronary intervention in patients with acute myocardial infarction (mi) in all kinds of clinical data. Results 15 patients after treatment with cardiopulmonary resuscitation (CPR) in all independent heart rate, breathing, gradually turned conscious. Interventional therapy group significantly shorter than the length of hospital stay and stable condition time thrombolysis group, left ventricular ejection fraction significantly greater than thrombolysis group (P<0.05). Conclusion Emergency percutaneous coronary intervention for acute myocardial infarction patients after cardiopulmonary resuscitation (CPR) is a reliable and safe treatment, worth clinical promotion.
【Key words】Emergency interventional therapy; acute myocardial infarction; cardiopulmonary resuscitation
心肺復(fù)蘇后急性心肌梗死由于受到諸多因素的限制,在治療方面存在一定困難。我院對(duì)收治的15例心肺復(fù)蘇后急性心肌梗死患者采取經(jīng)皮冠脈介入治療,取得良好療效,現(xiàn)報(bào)道如下。
1 資料與方法
1.1 一般資料
將我院2013年10月~2014年10月收治的行急診經(jīng)皮冠脈介入治療急性心肌梗死心肺復(fù)蘇后患者15例作為研究對(duì)象,其中男12例,女3例,年齡43~71歲,平均年齡(51.6±4.7)歲。15例患者行心肺復(fù)蘇前均確診為急性心肌梗死,患者從發(fā)病到心臟驟停的時(shí)間為2~3 h,其中發(fā)生在醫(yī)院內(nèi)13例,發(fā)生在來院途中的2例。同時(shí)選取我院同期收治的另外15例行靜脈溶栓治療的心肺復(fù)蘇后急性心肌梗死患者,15例患者經(jīng)診斷后均確診為急性心肌梗死,同時(shí)行心肺復(fù)蘇術(shù)成功后給予尿激酶溶栓治療。兩組一般資料比較差異無統(tǒng)計(jì)學(xué)意義(P>0.05)。
1.2 心肺復(fù)蘇方法
根據(jù)患者病情給予氣管插管、胸外心臟按壓、非同步電除顫、呼吸機(jī)輔助呼吸以及心肺復(fù)蘇藥物治療[1],其中10例患者經(jīng)電除顫后即成功復(fù)蘇,2例患者需給予呼吸機(jī)進(jìn)行輔助呼吸,4例給予氣管插管。15例患者經(jīng)心肺復(fù)蘇之后均恢復(fù)呼吸、神志轉(zhuǎn)清,再行急診經(jīng)皮冠脈介入治療,其中發(fā)生血壓偏低者3例,給予適量多巴胺靜滴入導(dǎo)管室。
1.3 經(jīng)皮冠脈介入治療
采用judkins法或橈動(dòng)脈穿刺法對(duì)15例患者行選擇性冠脈造影將患者左右冠脈情況顯示出來,經(jīng)多體位投照技術(shù)顯示梗死血管狀況,依據(jù)常規(guī)步驟對(duì)梗死相關(guān)血管行經(jīng)皮腔內(nèi)冠脈成形術(shù)+支架置入術(shù)[2]。需要注意的是,經(jīng)皮冠脈介入治療的標(biāo)準(zhǔn)就是患者殘余狹窄低于9.5%,前向血流為TiMi 3級(jí)[3]。
1.4 術(shù)前及術(shù)后處理
術(shù)前給予患者氯吡格雷280 mg、阿司匹林280 mg;手術(shù)過程中給予患者肝素120~140 IU/kg;其中6例患者術(shù)后留置動(dòng)脈鞘4天,1天后再次植入支架1枚。對(duì)患者手術(shù)后4~5天給予普通肝素850~1000 U/h靜