王紹錢+王徽+牛磊
[摘要] 目的 探討在保留內固定情況下,經(jīng)過換藥、病灶清除、擴創(chuàng)引流及使用敏感抗生素等一系列治療手段,治愈胸腰椎術后感染的可行性。 方法 回顧性分析2012年1月~2015年5月合肥市第二人民醫(yī)院收治的16例胸腰椎術后感染患者臨床資料。在保留內固定情況下,經(jīng)過一系列換藥、擴創(chuàng)、沖洗引流及使用敏感抗生素等積極治療,觀察切口愈合情況。對比分析治療前后白細胞(WBC)計數(shù)、血沉(ESR)、C-反應蛋白(CRP)及疼痛視覺模擬評分法(VAS)評分。 結果 所有患者切口愈合良好。隨訪6個月~2年,無患者復發(fā)。治療后WBC計數(shù)、ESR、CRP及VAS評分均較治療前降低,差異有統(tǒng)計學意義(P < 0.05)。 結論 應早期明確診斷胸腰椎術后感染,及時積極采取換藥、病灶清除、沖洗引流等積極治療,在保留內固定的情況下,也可獲得良好效果。
[關鍵詞] 胸腰椎;內固定;治療;白細胞計數(shù);血沉;C-反應蛋白
[中圖分類號] R681.530 [文獻標識碼] A [文章編號] 1673-7210(2018)01(c)-0081-04
[Abstract] Objective To explore the feasibility of treating postoperative infection of thoracolumbar spine in the case of retaining internal fixation with a series of treatment methods, such as changing drugs, removing the lesion, expanding the drainage and using sensitive antibiotics. Methods The clinical data of 16 patients with postoperative infection of thoracolumbar spine treated in the Second People's Hospital of Hefei from January 2012 to May 2015 were analyzed retrospectively. In the case of retaining internal fixation, after a series of treatment methods, such as changing drugs, removing the lesion, expanding the drainage and using sensitive antibiotics, the wound healing was observed. The white blood cell (WBC) number, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and visual analogous scale (VAS) were analyzed and compared before and after treatment. Results All patients wound healing were well. Follow-up time was from 6 months to 2 years, and no case recurred. After treatment, the WBC number, ESR, CRP and VAS score were lower than those before treatment, with statistically significant difference (P < 0.05). Conclusion It is necessary to clearly diagnose the postoperative infection of thoracolumbar spine in the early stage, and actively take the active treatment, such as changing drugs, removing the lesion, washing the drainage, etc. In the case of retaining internal fixation, it can also achieve good curative effect.
[Key words] Thoracolumbar spine; Internal fixation; Treatment; White blood cell count; Erythrocyte sedimentation rate; C-reactive protein
胸腰椎術后感染是脊柱外科常見且嚴重并發(fā)癥之一,隨著內固定裝置廣泛使用,診治不及時,感染可能會帶來災難性的后果[1]。胸腰椎術后感染往往會使患者痛苦增加,經(jīng)濟負擔加重,病程延長,療效變差,也會使病患對醫(yī)生、醫(yī)院的滿意度降低,也是醫(yī)患糾紛的潛在因素。脊柱內固定術后感染的治療可分3種:第一,長期換藥、抗感染治療;第二,取出內固定,病灶清除,沖洗引流,臥床制動,待感染控制后再植入或不植入內固定;第三,保留內固定,輔助換藥、病灶清除,沖洗引流,抗感染等一系列治療手段[2-3]。本文回顧性分析合肥市第二人民醫(yī)院(以下簡稱“我院”)骨科共收治的16例胸腰椎術后感染患者,在保留內固定裝置情況下,經(jīng)過一系列換藥、病灶清除,擴創(chuàng)沖洗引流(手術為1~3次),抗感染等治療的可行性。現(xiàn)將結果報道如下:
1 資料與方法
1.1 一般資料
選取我院2012年1月~2015年5月共收治的16例胸腰椎術后感染患者作為研究對象,其中,男10例,女6例;年齡30~65歲,平均46.5歲;胸12壓縮性骨折1例,腰1壓縮性骨折2例,腰1爆裂性骨折伴雙下肢不全癱1例,腰3爆裂性骨折1例,腰椎滑脫癥3例,腰椎間盤突出癥4例,腰椎管狹窄癥4例。表淺感染6例,深部感染10例,感染發(fā)生時間為術后第6~20天。endprint