林小容 林崇光 楊曉麗

[摘要] 目的 探討正念認(rèn)知干預(yù)對(duì)雙相情感障礙（BAD）患者心理健康狀況及生活質(zhì)量的影響。 方法 選擇2016年1月～2017年12月該院精神科就診的BAD患者共100例，隨機(jī)分為干預(yù)組和對(duì)照組。兩組均予以丙戊酸鈉片治療，起始劑量400 mg/d，逐漸加量增至800～1600 mg/d。對(duì)照組在藥物治療基礎(chǔ)上采用常規(guī)干預(yù)措施，干預(yù)組再加正念認(rèn)知干預(yù)，兩組均干預(yù)12周。觀察兩組干預(yù)前后心理健康狀況及生活質(zhì)量變化，并評(píng)估其臨床效果。 結(jié)果干預(yù)12周后，兩組患者SAS和SDS評(píng)分均較干預(yù)前明顯下降（P<0.05或P<0.01），且干預(yù)組下降幅度較對(duì)照組更顯著（P<0.05）;干預(yù)12周后，兩組生活質(zhì)量SF-36評(píng)分均較治療前明顯上升（P<0.05或P<0.01），且干預(yù)組上升幅度較對(duì)照組更顯著（P<0.05）。 結(jié)論 正念認(rèn)知干預(yù)BAD患者能明顯的改善患者的心理健康狀況，提高患者的生活質(zhì)量。

[關(guān)鍵詞] 雙相情感障礙;正念認(rèn)知干預(yù);心理健康狀況;生活質(zhì)量

[中圖分類(lèi)號(hào)] R749.05? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] B? ? ? ? ? [文章編號(hào)] 1673-9701（2019）09-0077-04

[Abstract] Objective To investigate the effect of mindfulness cognitive intervention on mental health status and quality of life in patients with bipolar affective disorder（BAD）. Methods A total of 100 patients with BAD who were admitted to the department of psychiatry in our hospital from January 2016 to December 2017 were selected and randomly divided into intervention group and control group. Both groups were given sodium valproate tablets.The initial dose was 400 mg/d， which was gradually increased to 800-1600 mg/d.The control group was given routine interventions based on drug treatment. The intervention group was further given mindfulness cognitive intervention， and both groups were intervened for 12 weeks. The mental health status and quality of life changes before and after intervention were observed and the clinical effects were evaluated in both groups. Results After 12 weeks of intervention， the SAS and SDS scores of the two groups were significantly lower than those before the intervention（P<0.05 or P<0.01）， and the decrease in the intervention group was more significant than that in the control group（P<0.05）; after 12 weeks of intervention， the quality of life SF-36 scores of the two groups were significantly higher than those before treatment（P<0.05 or P<0.01）， and the increase in the intervention group was more significant than that in the control group（P<0.05）. Conclusion Mindfulness cognitive intervention in the patients with BAD can significantly improve the mental health status of patients and improve their quality of life.

[Key words] Bipolar affective disorder （BAD）; Mindfulness cognitive intervention; Mental health status; Quality of life

雙相情感障礙（Bipolar affective disorder，BAD）是精神科常見(jiàn)疾病之一，具有患病率高、自殺率高和誤診率高等特點(diǎn)[1，2]。BAD可表現(xiàn)為抑郁、焦慮、躁狂等心理問(wèn)題，目前臨床上對(duì)于BAD重視不夠，常誤診為單相抑郁，導(dǎo)致患者病情加重，引起患者社會(huì)功能和生活質(zhì)量下降[3，4]。因此采用有效的藥物和康復(fù)干預(yù)是改善BAD患者的心理健康和生活質(zhì)量的關(guān)鍵措施[5，6]。正念認(rèn)知干預(yù)是一種應(yīng)用于情緒調(diào)節(jié)、壓力緩解的干預(yù)措施，近年來(lái)逐漸應(yīng)用于BAD干預(yù)治療中[7]。本研究觀察了正念認(rèn)知干預(yù)對(duì)雙相情感障礙患者心理健康狀況及生活質(zhì)量的影響，現(xiàn)報(bào)道如下。