張旭坤 王勝利 葛站勇
摘要:目的? 探究前外側(cè)入路下不同髖關(guān)節(jié)置換方式治療老年股骨頸骨折的臨床效果。方法? 選取2018年1月~2019年12月我院收治的老年股骨頸骨折患者100例,根據(jù)前外側(cè)入路下髖關(guān)節(jié)置換方式不同分為研究組與對(duì)照組,各50例。對(duì)照組予前外側(cè)入路下半髖關(guān)節(jié)置換方式,研究組予前外側(cè)入路下全髖關(guān)節(jié)置換方式,比較比較兩組臨床指標(biāo)(手術(shù)時(shí)間、住院時(shí)間、出血量、切口長(zhǎng)度)、骨代謝指標(biāo)[骨特異性堿性磷酸酶(BAP)、骨該素(BGP)、Ⅰ型膠原羧基端肽(β-CTX)]、炎癥因子指標(biāo)[腫瘤壞死因子α(TNF-α)、白介素-1(IL-1)]。結(jié)果? 研究組手術(shù)時(shí)間、住院時(shí)間、出血量?jī)?yōu)于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05);研究組BAP、BGP水平高于對(duì)照組[(42.01±5.31)ng/ml vs(33.14±4.69)ng/ml]、[(9.59±1.21)ng/ml vs(8.75±0.92)ng/ml],β-CTX水平低于對(duì)照組[(201.89±38.32)pg/ml vs(310.77±40.06)pg/ml],差異有統(tǒng)計(jì)學(xué)意義(P<0.05);研究組TNF-α、IL-1水平低于對(duì)照組[(12.56±2.01)pg/ml vs(18.56±2.34)pg/ml]、[(3.01±0.29)pg/ml vs(4.21±0.54)pg/ml],差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論? 在老年股骨頸骨折中采用前外側(cè)入路下全髖關(guān)節(jié)置換方式雖手術(shù)時(shí)間較長(zhǎng),但治療效果更佳,能有效促進(jìn)骨代謝與再生,改善炎癥,有利于患者恢復(fù)。
關(guān)鍵詞:前外側(cè)入路;半髖關(guān)節(jié)置換;全髖關(guān)節(jié)置換;股骨頸骨折
中圖分類號(hào):R683? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 文獻(xiàn)標(biāo)識(shí)碼:A? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? DOI:10.3969/j.issn.1006-1959.2020.22.034
文章編號(hào):1006-1959(2020)22-0120-03
Comparison of Curative Effect Different Hip Replacement Methods in the Treatment
of Femoral Neck Fracture in the Elderly Through Anterolateral Approach
ZHANG Xu-kun,WANG Sheng-li,GE Zhan-yong
(Department of Orthopaedics,Tianjin Jinnan Hospital,Tianjin 300350,China)
Abstract:Objective? To explore the clinical effect of different hip replacement methods under anterolateral approach in the treatment of femoral neck fracture in the elderly.Methods? from January 2018 to December 2019, 100 elderly patients with femoral neck fracture were selected and divided into study group and control group according to the different ways of hip replacement under anterolateral approach, 50 cases in each group.The control group received anterolateral approach for lower hemi hip replacement, and the study group received anterolateral approach for total hip replacement. The clinical indicators (operating time, hospital stay, blood loss, incision length) and bone metabolism were compared between the two groups. Indexes [Bone-specific alkaline phosphatase (BAP), Bone (BGP), Type I collagen carboxy-terminal peptide (β-CTX)], inflammatory factor indexes [Tumor necrosis factor α (TNF-α), interleukin-1 (IL-1)].Results? The operation time, hospitalization time, blood loss of the study group were better than those of the control group,the difference was statistically significant (P<0.05); the BAP and BGP levels of the study group were higher than those of the control group [(42.01±5.31)ng/ml vs (33.14±4.69) ng/ml], [(9.59±1.21) ng/ml vs (8.75±0.92) ng/ml], the level of β-CTX was lower than that of the control group [(201.89±38.32) pg/ml vs ( 310.77±40.06)pg/ml], the difference was statistically significant (P<0.05); the levels of TNF-α and IL-1 in the study group were lower than those in the control group [(12.56±2.01)pg/ml vs (18.56±2.34)pg /ml], [(3.01±0.29) pg/ml vs (4.21±0.54) pg/ml], the difference was statistically significant (P<0.05).Conclusion? The total hip replacement with anterolateral approach in the elderly patients with femoral neck fracture has a long operation time, but the treatment effect is better. It can effectively promote bone metabolism and regeneration, improve inflammation, and help patients recover.
綜上所述,在老年FNF中采用前外側(cè)入路下全髖關(guān)節(jié)置換方式雖手術(shù)時(shí)間較長(zhǎng),但治療效果更佳,能有效促進(jìn)骨代謝與再生,改善炎癥,有利于患者恢復(fù)。
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收稿日期:2020-04-16;修回日期:2020-05-02
編輯/杜帆
作者簡(jiǎn)介:張旭坤(1978.9-),男,河北石家莊人,本科,主治醫(yī)師,主要從事創(chuàng)傷關(guān)節(jié)的研究工作